Tupelo lost an opponent and picked one up shortly thereafter after their scheduled opponent had to cancel due to quarnatine on Tuesday.
North Panola will instead travel to Tupelo on Friday.
This will be the first meeting between the two teams.
North Panola, a 3A power, is 1-1 on the season after defeating Calhoun City last week.
Tupelo will be looking for their first win of the season.